Typhoid Antigen Test

Short Description:

CAT # PRODUCT DESCRIPTION SPECIMEN CUT-OFF SENSITIVITY SPECIFICITY ACCURACY FORMAT KIT SIZE RI801C Typhoid IgG/IgM IgG and IgM antibodies to Salmonella typhoid and Para-typhoid 3-line Test Serum/Plasma N/A IgG:91.8% IgM:92.7% IgG:98.7% IgM:98.8% IgG:97.5% IgM:97.6% Cassette 25T RI824C s.Typhi Ag Salmonella Typhoid Antigen Test (S.typhoid) Stool/serum/plasma N/A 97.40% 98.70% 98.10% Cassette 25T Typhoid fever is a serious illness caused by a ba...


Product Detail

Product Tags

Product Parameters

CAT # PRODUCT DESCRIPTION SPECIMEN CUT-OFF SENSITIVITY SPECIFICITY ACCURACY FORMAT KIT SIZE

RI801C

Typhoid IgG/IgM

IgG and IgM antibodies to Salmonella typhoid and Para-typhoid 3-line Test

Serum/Plasma

N/A

IgG:91.8% IgM:92.7%

IgG:98.7% IgM:98.8%

IgG:97.5% IgM:97.6%

Cassette

25T

RI824C

s.Typhi Ag

Salmonella Typhoid Antigen Test (S.typhoid)

Stool/serum/plasma

N/A

97.40%

98.70%

98.10%

Cassette

25T

Summary

Typhoid fever is a serious illness caused by a bacterium called Salmonella Typhi. Typhoid fever affects more than 16 million persons each year and 600,000 associated deaths occur annually. Its incidence is highest in children and young adults between 5 and 19 years old.1 Typhoid fever is spread by eating or drinking contaminated food or water or by direct or indirect contact with fecal material from infected persons.2 Symptoms of Typhoid infection may be mild to severe, and may include fever, headache, loss of appetite, constipation or diarrhea, and nonproductive cough. The symptoms may appear 3 days to 3 months, but onset of illness usually occurs 1-3 weeks after exposure.2,3 The clinical diagnosis of Typhoid fever depends on the separation of Salmonella typhi (S. typhi) and Paratyphi from blood, bone marrow or a specific anatomic lesion in the facilities that cannot afford to perform this complicated and time-consuming process. Widal Test is used to facilitate the diagnosis. However, many limitations lead to difficulties in the interpretation of Widal Test. EUGENE® Typhoid IgG/IgM Rapid Test is an immunochromatographic assay that detects the IgG and IgM antibodies to Salmonella typhi (S. typhi) and Paratyphi in human whole blood, serum or plasma. It is simple, easy to perform and helpful in the determination of current and previous infection by the Typhoid.

Test Principle

The EUGENE® Typhoid IgG/IgM Rapid Test is a lateral flow immunochromatographic assay. The membrane strip in device contains 3 pre-coated lines: “G”-Test line for Typhoid IgG; “M”-Test line for Typhoid IgM; and control line. During testing, the specimen added into the sample pad of the test strip migrates by capillary action across the membrane strip. Typhoid IgM and/or IgG antibodies if present in the specimen react with the salmonella H and O antigens of colloidal gold conjugates and forms an immunocomplex, which migrates alone the test strip, and then captured by the pre-coated lines of anti-human IgG or anti-human IgM. If the red colored G appears, it indicates a result of Typhoid IgG positive. If the red colored M appears, it indicates a result of Typhoid IgM positive. Absence of any of the G-line or M-line suggests a negative Typhoid IgG or Typhoid IgM result. The test contains an internal control line which should exhibit a red line regardless of the color development on any of the test lines. Otherwise, the test result is invalid and the test must be repeated with a new test device.

Principle

The EUGENE® S. Typhi Ag Rapid Test is a qualitative, lateral flow immunoassay for the detection of Salmonella Typhi antigen in human stool, serum or plasma specimen. The membrane of the test strip contained in the cassette device is pre-coated with anti-Salmonella antibodies on the test line region of the strip. During testing, the stool, serum or plasma specimen reacts with the particle coated with anti-Salmonella antibody. The mixture migrates upward on the membrane chromatographically by capillary action to react with anti-Salmonella antibodies on the membrane and generate a colored test line (T). The presence of this colored line in the test region indicates a positive result, while its absence indicates a negative result. To serve as a procedural control, a colored control line (C) will always appear in the control line region indicating that proper volume of specimen has been added and membrane wicking has occurred.


  • Previous:
  • Next:

  • Related Products